翻訳と辞書 Words near each other ・ Nucleic acid analogue ・ Nucleic acid design ・ Nucleic acid double helix ・ Nucleic acid hybridization ・ Nucleic acid inhibitor ・ Nucleic acid metabolism ・ Nucleic acid methods ・ Nucleic acid nomenclature ・ Nucleic acid notation ・ Nucleic acid quantitation ・ Nucleic acid quaternary structure ・ Nucleic acid secondary structure ・ Nucleic acid sequence ・ Nucleic acid structure ・ Nucleic acid structure determination ・ Nucleic acid structure prediction ・ Nucleic acid templated chemistry ・ Nucleic acid tertiary structure ・ Nucleic acid test ・ Nucleic acid thermodynamics ・ Nucleic Acids Research ・ Nucleo Operativo Centrale di Sicurezza ・ Nucleobase ・ Nucleobase cation symporter-1 ・ Nucleobase cation symporter-2 ・ Nucleocosmochronology ・ Nucleocosmogenesis ・ Nucleocytoplasmic large DNA viruses ・ Nucleofection ・ Nucleofuge Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Nucleic acid structure prediction ： ウィキペディア英語版 Nucleic acid structure prediction Nucleic acid structure prediction is a computational method to determine nucleic acid secondary and tertiary structure from its sequence. Secondary structure can be predicted from a single or from several nucleic acid sequences. Tertiary structure can be predicted from the sequence, or by comparative modeling (when the structure of a homologous sequence is known). The problem of predicting nucleic acid secondary structure is dependent mainly on base pairing and base stacking interactions; many molecules have several possible three-dimensional structures, so predicting these structures remains out of reach unless obvious sequence and functional similarity to a known class of nucleic acid molecules, such as transfer RNA or microRNA, is observed. Many secondary structure prediction methods rely on variations of dynamic programming and therefore are unable to efficiently identify pseudoknots. While the methods are similar, there are slight differences in the approaches to RNA and DNA structure prediction. ''In vivo'', DNA structures are more likely to be duplexes with full complementarity between two strands, while RNA structures are more likely to fold into complex secondary and tertiary structures such as in the ribosome, spliceosome, or tRNA. This is partially because the extra oxygen in RNA increases the propensity for hydrogen bonding in the nucleic acid backbone. The energy parameters are also different for the two nucleic acids. ==Single sequence structure prediction== A common problem for researchers working with RNA is to determine the three-dimensional structure of the molecule given just the nucleic acid sequence. However, in the case of RNA much of the final structure is determined by the secondary structure or intra-molecular base-pairing interactions of the molecule. This is shown by the high conservation of base-pairings across diverse species. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nucleic acid structure prediction」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.